Vitamin C — Needed More Than Ever

With the continued media bombardment regarding public health concerns about H1N1 flu virus, it seemed appropriate to revisit what Dr. Carey Reams discovered regarding vitamin C and its importance in supporting body chemistry for “perfect” wellness. Dr. Reams stated that to have “perfect health” one’s blood must maintain 4500 parts per million of vitamin C per liter of blood over a 24 hour period. This amount could also be expressed as milligrams (mg) per liter and mean the same thing. So, how can one maintain this level of vitamin C?

Whole blood has two constituents, plasma (liquid part) and blood cells (cellular part). There is a unique relationship that exists between the blood cells and the plasma containing them such that red blood cells (RBCs) can concentrate vitamin C up to 50 times what is contained in the plasma surrounding them.

Unlike most animals and plants, man, along with guinea pigs, are among the few animals that don’t produce their own vitamin C. For example, an adult goat, a typical example of a vitamin C-producing animal, will manufacture more than 13 g of vitamin C per day in “normal” health and the biosynthesis will increase to as much as 100 grams (100,000mgs) under stress. Whereas, we humans must obtain every bit of our vitamin C from our diet on a regular daily basis. This is because we humans have a “defective” gene that prevents the last of four steps in the process of converting glucose to vitamin C from taking place. Humans are genetically unable to produce a liver enzyme called gulanolactone oxidase needed for the fourth and final step in manufacturing vitamin C.

Vitamin C exists in two forms in the plasma, either as ascorbic acid or dehydroascorbate (also referred to as DHA). The ascorbic acid is the active non-oxidized (or “reduced”) form, which is why there is so much interest in it as an anti-oxidant, while the dehydroascorbic acid (DHA) is the nonactive “oxidized” form. Researchers have demonstrated that in a so-called healthy — though not according to RBTI standards — individual, there is in the plasma an ongoing dynamic ratio between the two forms of vitamin C, with the ascorbic acid very significantly predominating at about 14-15:1. On the other hand, in various disease conditions, such as Pyogenic meningitis for example, the ratios were found to be as low as  0.7:1. In other words, the active ascorbic acid, in disease and toxic states, is so low that the person would be considered as having scurvy. Research has demonstrated that during illness, injury and toxic poisoning people require up to 1000 times the levels absorbed by healthy individuals due to the great deficiency. Yes, healthy individuals have obtained sufficient Vitamin C from (quality food) however, truth be known this can be  a rare find due to the  often found poor quality of our foods today.

In his book Vitamin C and Cancer, Dr. Abraham Hoffer writes how Dr. Riordan, a leading researcher into cancer and vitamin C, came to understand the increased need for vitamin C in times of stress and this experience was one of the factors that led to his interest in the substance. As part of a research study, Riordan’s own vitamin C blood levels were being measured on a regular basis. His plasma levels were in the typical range of 13 to 17mg per liter. However, during the time of the experiment, a spider bit him on the thigh. He was surprised to find that his blood levels subsequently dropped to undetectable values. Thinking it would be easy to bring his levels back to the normal range, he asked a nurse to give him 15 grams of sodium ascorbate intravenously — a large dose. The next day his blood levels were still undetectable. Amazed, Dr. Riordan repeated the 15 gram injection, with the same result. He continued to repeat the cycle for five days, when his blood level became detectable but was still in the range typical of deficiency. It was several more days before his vitamin C level returned to normal and the spider bite was completely healed. This is an example of how a minor injury required more than 75 grams of vitamin C, given intravenously, before “normal” blood levels were restored.

In RBTI terms, this means that keeping one’s numbers in the “healing” range A, with plenty of vitamin C in the daily diet, is the only way to be assured that an active reservoir of the ascorbic acid form of vitamin C can be maintained in the plasma. On the other hand, if the RBTI chemistry is in one of the other ranges, this would be an indication that ascorbic acid form of vitamin C in the plasma may be practically non existent, allowing the DHA inactive form to dominate.

There appears to be an interesting and challenging caveat, however. Research has shown that ascorbic acid has a half-life in the blood plasma of about 30 minutes. This means that every 30 minutes half the remaining amount of ascorbic acid in the blood is excreted through the kidneys. It is this high turnover rate which makes it extremely challenging for the body to maintain an ideal ascorbic acid reservoir (4500 ppm) in the blood that is able to deal with the “oxidizing” affects of dis-ease causing chemistry, i.e., demonstrated by RBTI numbers outside of range A.

On the other hand, there is a redeeming factor in this short half-life. First, there is also a rapid excretion of the DHA (oxidized) form of ascorbic acid. Second, there are pumps within the kidneys that reabsorb ascorbic acid, but not DHA. This process works in favor of increasing the ratio of ascorbic acid to DHA, providing the dietary consumption of vitamin C is in the form and amount in agreement with the RBTI chemistry.

Very interestingly recent research has shown that humans, and their animal counter parts that cannot manufacture their own vitamin C, have a unique recycling system for the inactive DHA form of vitamin C in order to keep the active ascorbic acid form of vitamin C in predominance within the plasma as well as body tissues and cells.

Human red blood cells (RBCs), which make up as much as 45% of blood volume, absorb DHA from the plasma. They can absorb up to 50 times more per volume than the plasma can contain. Once inside the RBC the oxidized DHA is converted back to non-oxidized (reduced) ascorbic acid where it can be efficiently carried through the bloodstream to supply the rest of the body’s cellular needs. In comparison, research has also shown that in animals that manufacture vitamin C, their RBCs are unable to pick up DHA. Plus, humans, along with animals that likewise do not manufacture their own vitamin C, have a special cell membrane protein called Glut1, which is responsible for transporting into the cell not only glucose but also DHA due to their structural similarities. What’s more, human RBCs have more Glut1 than any other cell type and Glut1 also strongly favors DHA over glucose. Interestingly, Glut1 is missing in animals that manufacture all their needed vitamin C.

The brain illustrates the body’s unique way of recycling vitamin C. The brain is one of the organs that contains one of the highest amounts of vitamin C of any organ in the body.  Yet, the active form of vitamin C cannot pass the blood brain barrier. Instead it is dehydroascorbate (DHA) that is transported through the blood-brain barrier via Glut1 transporters, and then converted to vitamin C after it is transported.

From this it does not take much of a stretch of our RBTI chemistry knowledge to see why excess sugar in the blood or tissue can improperly dominate Glut1’s function and interfere with vitamin C’s proper uptake, distribution and utilization. Vitamin C research certainly is substantiating that the further RBTI chemistry is away from range A (they call it “oxidative stress”), the more DHA (oxidized) form of vitamin C will predominate throughout tissues. While the closer RBTI chemistry is to range A, the greater the potential for nonoxidized active form of vitamin C to predominate in and through tissues. The ratio of nonoxidized to oxidized is central to the action of vitamin C, while how much is available in the blood at any given time for the health of the tissue is directly related to the amount in the diet and whether the RBTI chemistry will promote or detract from its uptake, distribution and utilization.

Dr. Reams taught two ways of supplementing vitamin C in the diet; 1) ascorbic acid supplements, both natural and otherwise, but only according to the test “numbers;”  2) stewed onions. Ascorbic acid, because of being a strong cation, can only be used as long as the pH of the urine was above 6.20. If the pH were below 6.20, then he would recommend stewed onions or soup from stewed onions. Yet, an ever expanding research interest in the real disease suppressing and curing value behind high level vitamin C supplementation (mega doses) has also provided some very valuable new information that can certainly add to the RBTI student’s working knowledge and understanding. For example, cell culture studies at the National Institute of Health demonstrate that 350-400mg/dL of vitamin C show optimal cytotoxic effects on cancer cells. When we transpose Dr. Reams’ 4500 ppm per liter of blood into to mg/dL we find that it is equivalent to 450 mg/dL. Thus, optimum vitamin C levels in RBTI range A means that diseased cells and organisms can be literally destroyed by vitamin C present in the blood.

We can also learn from research that there is a right and wrong way to take vitamin C. For example, since the half-life (the time it takes for half of a substance to be excreted) of vitamin C in the blood is 30 minutes, taking mega doses infrequently is not best if one is attempting to maintain a continuous maximum blood level. Indeed, research verifies that five 100mg doses taken at intervals through the day would raise average blood levels more than a single one-gram does. The best way is to take smaller amounts at regular intervals, say 250-500 mg every 4 or 6 hours, throughout the day according to the RBTI “numbers.”

Since vitamin C is absorbed actively from all areas of the gut, using a time-release form may be of value in some cases where a strong cationic affect from C is not needed. Furthermore, using mineral ascorbates can be beneficial where there is a concern for causing a pH drop with vitamin C. Contrary to previous beliefs, when mineral ascorbates, i.e., calcium ascorbate, potassium ascorbate etc., make contact with the stomach acids their conversion to ascorbic acid and mineral ions do not add to the volume of acid in the digestion according to research. When mineral ascorbates have appeared to cause digestive upsets, research has demonstrated that it is the osmotic gradient that has been altered in the gut not the pH. When blood plasma is not able to take on more C, there is an osmotic movement of water toward the ascorbate in the gut, which means water will move into the gut and liquefy the stool, causing diarrhea.

Vitamin C has been considered one of the most important essential nutrients in our diet since the discovery in 1907 that it prevents scurvy. In addition, vitamin C has several important functions in our body for the synthesis of amino acids and collagen, wound healing, metabolism of iron, lipids and cholesterol and others. With the ever-increasing interest in the importance of “anti-oxidants” in disease prevention, vitamin C continues to attract research attention for the key role it plays in this regard.

Thus, it is certainly possible to keep your blood levels of C at or near the optimum of 4500ppm by understanding your RBTI chemistry as it dictates your diet and supplementation patterns to maintain “perfect health” no matter what public health challenges one might be exposed to.

Biological tissues that accumulate over 100 times the level in blood plasma of vitamin C are the adrenal glands, pituitary, thymus, corpus luteum and retina. Those with 10 to 50 times the concentration present in blood plasma include the brain, spleen, lung, testicle, lymph nodes, liver, thyroid, small intestinal mucosa, leukocytes, pancreas, kidney and salivary glands.

Vitamin C Breakthrough

Of the many projects that Dr. Reams was desirous of completing before his death, developing an anionic (alkaline reacting) vitamin C was an important one. But little did he realize that within 30 years of his passing a method would be discovered making it possible for anyone to maintain high blood levels of vitamin C in spite of their RBTI chemistry. Yes, it is now possible to take water soluble vitamin C orally because of what is known as liposome encapsulation. This method of delivery allows vitamin C (ascorbic acid) to be delivered directly to the blood and then to the cell without  negatively altering the digestive or blood chemistry. Liposome encapsulated vitamin C is 100% absorbed into the blood and delivered directly into the cell because the microscopic liposome capsule is identical to the material the cell wall is made of. Like attracts like. Dr. Reams would have praised God for this discovery. Lypo-Spheric Vitamin C now makes it possible for anyone to maintain a high blood level of vitamin C while moving their RBTI electrochemistry toward Range A.

Here are some fascinating facts about vitamin C that Dr. Reams discovered:

  • Vitamin C is the vital cement that holds the cells of the body’s tissues together.
  • The disease leprosy is actually an expression of a type of scurvy, vitamin C deficiency such that the cells of the body are coming apart for lack of vitamin C to keep them cemented together.
  • If the blood can maintain 4,500 mg of vitamin C per liter or 450 mg/dl (i.e., 4,500 ppm concentration), perfect health could be realized, because vitamin C can then be the perfect dis-ease “policing” substance of the body.
  • As the levels of available vitamin C in the blood decrease, so does the reserve mineral energy level.
  • The ascorbic acid form of vitamin C is acidic and should not be used when urine pH is below 6.20.
  • The urine chemistry must have a pH greater than or equal to 6.20 or the body’s cells cannot accept vitamin C.
  • Stewed onions are the richest source of non-acidic vitamin C that the body can easily use when the pH of the urine is below 6.20.
  • The body can store vitamin C, contrary to what science has said.
  • Natural pancreatic insulin is necessary for vitamin C utilization, but excess insulin (natural or synthetic) is an enemy of vitamin C.
  • When calciums are out of ratio, as shown by the urine and saliva pH, it indicates a vitamin C deficiency.
  • When the conductivity of the urine becomes excessive, this shows that vitamin C is being destroyed.
  • When the body’s oxygen, calcium, iron and iodine are deficient, this causes a critical vitamin C deficiency which is the basis of all so-called “collagen diseases.”
  • “Stretch marks” are a classic sign of vitamin C deficiency.
  • A vitamin C deficiency means a vitamin A deficiency.
  • Taking vitamin C orally is not a guarantee that your body will properly accept and use it. RBTI test numbers must be understood in order to know how to properly supplement vitamin C.

Thanks for stopping by.

Dr. A.F. Beddoe, D.D.S. 

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